Gene interactions and pathways from curated databases and text-mining

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MIP — PI3

Text-mined interactions from Literome

Darieva et al., J Leukoc Biol 2004 (Inflammation...) : Specific pharmacological inhibition of the PI-3K , c-jun-N-terminal kinase ( JNK ), and to a smaller extent, p38 MAPK but not extracellular regulated kinase (ERK), suppressed NF-kappaB dependent reporter gene transcription and MIP-2 and NO secretion in BCG induced RAW264.7 macrophages
Watson et al., Mol Pharmacol 2005 (MAP Kinase Signaling System) : MIP-2 activated extracellular signal regulated kinase ( ERK ) 1/2 and Akt and both the mitogen activated protein kinase kinase 1 ( MEK1 ) and phosphatidylinositol 3-kinase (PI3K) inhibitors 2'-amino-3'-methoxyflavone ( PD98059 ) and wortmannin reduced the neuroprotective effect of MIP-2