Gene interactions and pathways from curated databases and text-mining

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PI3 — PRL

Text-mined interactions from Literome

Amaral et al., Horm Metab Res 2003 : PRL induced IRS-2 phosphorylation and its association with PI 3-kinase did not add to the effect of insulin
Hügl et al., JOP : Journal of the pancreas 2007 (Insulinoma) : Prolactin activated the JAK2/STAT5 pathway and phosphatidylinositol-3'-kinase (PI3'K) in the presence of all the glucose concentrations used ( 3-15 mM )
Di Rosa et al., J Cell Biochem 2009 (MAP Kinase Signaling System) : Prolactin induces chitotriosidase expression in human macrophages through PTK, PI3-K , and MAPK pathways
al-Sakkaf et al., J Mol Endocrinol 1997 : Our previous studies indicated that PI3-kinase is involved in prolactin (PRL) signalling ... These data provide evidence that PRL induced activation of PI3-kinase may be mediated by the tyrosine phosphorylation of fyn in Nb2 cells