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PI3 — RHO

Text-mined interactions from Literome

Lee et al., Molecular vision 2003 : These data indicate that CECs in culture have constitutively active Rho activity as evidenced by stress fiber formation and that PI 3-kinase negatively regulates the formation of stress fibers and focal adhesions, perhaps antagonizing the Rho pathways
Zhai et al., J Neurooncol 2006 (Brain Neoplasms...) : Our findings suggest that activation of Rho signaling via PI-3K is required for radiation induced invasion, although not required for invasion under physiologic conditions
Butcher et al., Dev Biol 2007 : Both Rho and PI 3-kinase were involved in normal cushion mesenchyme matrix compaction, but only PI 3-kinase was required for the enhanced matrix compaction due to periostin
Strumane et al., Leuk Res 2008 (Disease Progression...) : PI3-kinase may also activate Rho-GTPases and their regulatory GEFs to promote invasion
Torre et al., Arch Otolaryngol Head Neck Surg 2010 (Carcinoma, Squamous Cell...) : On the other hand, the presence of Y-27632, a Rho kinase inhibitor, and LY-294002, a PI-3 kinase inhibitor , blocked HA-mediated cisplatin resistance by HNSCC
Zhang et al., J Biol Chem 1995 : We conclude that Rho and G beta gamma each, respectively, contributes to the activation of different PI 3-Ks ( p85 containing heterodimer and PI 3-K (gamma) ) in thrombin stimulated platelets