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IFNG — UGCG

Text-mined interactions from Literome

Hu et al., J Immunol 2003 : We investigated whether GCs could also block activation of Janus kinase-STAT signaling by IFN-gamma , a potent proinflammatory cytokine ... GCs inhibited IFN-gamma-inducible gene expression, thus demonstrating the physiological significance of inhibition of signal transduction
Elenkov et al., Ann N Y Acad Sci 2004 (Immune System Diseases...) : Evidence accumulated over the last 5-10 years indicates that glucocorticoids (GCs) inhibit the production of interleukin (IL)-12, interferon (IFN)-gamma , IFN-alpha, and tumor necrosis factor (TNF)-alpha by antigen presenting cells (APCs) and T helper ( Th ) 1 cells, but upregulate the production of IL-4, IL-10, and IL-13 by Th2 cells