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RHOA — TAT
Text-mined interactions from Literome
Urbinati et al., J Cell Sci 2005
:
Also, alpha ( v ) beta ( 3 )
/Tat interaction
triggers the activation of focal adhesion kinase,
RhoA and pp60src ... Finally, the activation of focal adhesion kinase,
RhoA , NF-kappaB and pp60src are
required to mediate the motogenic activity of
Tat in endothelial cells
Nakakuki et al., Arterioscler Thromb Vasc Biol 2005
(Atherosclerosis...) :
Pretreatment with
TAT-C3 ( a membrane-permeable
RhoA inhibitor ) and Y-27632 ( Rho-kinase inhibitor ) significantly inhibited CRP induced PAI-1 expression
Guilluy et al., J Biol Chem 2007
(Anoxia...) :
5-HT promotes the association of
RhoA with the E3 ubiquitin ligase Smurf1, and 5-HT induced RhoA depletion was
inhibited by the proteasome inhibitor MG132 and the RhoA inhibitor
Tat-C3
Zhong et al., J Cereb Blood Flow Metab 2010
:
Disruption of lipid rafts by depletion of membrane cholesterol by methyl-beta-cyclodextrin, but not caveolin-1 silencing, also abolished
Tat mediated
RhoA activation and P-gp upregulation