Gene interactions and pathways from curated databases and text-mining

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RHOA — TAT

Text-mined interactions from Literome

Urbinati et al., J Cell Sci 2005 : Also, alpha ( v ) beta ( 3 ) /Tat interaction triggers the activation of focal adhesion kinase, RhoA and pp60src ... Finally, the activation of focal adhesion kinase, RhoA , NF-kappaB and pp60src are required to mediate the motogenic activity of Tat in endothelial cells
Nakakuki et al., Arterioscler Thromb Vasc Biol 2005 (Atherosclerosis...) : Pretreatment with TAT-C3 ( a membrane-permeable RhoA inhibitor ) and Y-27632 ( Rho-kinase inhibitor ) significantly inhibited CRP induced PAI-1 expression
Guilluy et al., J Biol Chem 2007 (Anoxia...) : 5-HT promotes the association of RhoA with the E3 ubiquitin ligase Smurf1, and 5-HT induced RhoA depletion was inhibited by the proteasome inhibitor MG132 and the RhoA inhibitor Tat-C3
Zhong et al., J Cereb Blood Flow Metab 2010 : Disruption of lipid rafts by depletion of membrane cholesterol by methyl-beta-cyclodextrin, but not caveolin-1 silencing, also abolished Tat mediated RhoA activation and P-gp upregulation