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CSK — EGF
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Dewar et al., Mol Pharmacol 2007
(Calcium Signaling) :
Ciglitazone rapidly activates extracellular signal regulated kinase ( Erk ) MAPK, an event requiring
c-Src kinase dependent
epidermal growth factor receptor (EGFR) transactivation, whereas troglitazone only weakly activates Erk and does not induce EGFR transactivation ; the mechanism underlying this difference remains unclear
Brunton et al., Oncogene 1997
(Adenoma...) :
This increased motility was accompanied by an
EGF induced increase in
c-Src kinase activity, relocalisation of c-Src to the cell periphery and phosphorylation of FAK in the carcinoma cells but not in the adenoma cells