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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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PTBP1 — TGFB1

Text-mined interactions from Literome

Strobl et al., Microbes Infect 1999 : TGF-beta1 inhibits upregulation of critical T-cell costimulatory molecules on the surface of DCs and reduces the antigen presenting capacity of DCs
Sato et al., J Immunol 2000 : Stimulation of mature DCs with TGF-beta 1 also enhanced TNF-alpha induced down-regulation of the expressions of CCR-1, CCR-3, CCR-5, CCR-6, and CXCR-4, and chemotaxis to their respective ligands, while this stimulation suppressed TNF-alpha induced expression of CCR-7 and chemotactic migratory ability to MIP-3 beta
Luo et al., Proc Natl Acad Sci U S A 2007 (Diabetes Mellitus, Type 1) : Here we show that beta-cell peptide pulsed dendritic cells (DCs) from nonobese diabetic ( NOD ) mice can effectively induce CD4 ( + ) CD25 ( + ) Foxp3 ( + ) T cells from naïve islet-specific CD4 ( + ) CD25 ( - ) T cells in the presence of TGF-beta1
Ojima et al., Int J Oncol 2007 : Furthermore, the transduction of the GM-CSF gene into DCs also suppressed the incidence of apoptosis of DCs induced by transforming growth factor-beta1 ( TGFbeta-1 )
Dumitriu et al., J Immunol 2009 (Carcinoma, Non-Small-Cell Lung...) : Using gene expression analysis, we found that human DCs increased the expression of TGF-beta1 transcripts following culture with human lung carcinoma cells ( LCCs )
Kushwah et al., J Immunol 2009 : Additionally, apoptotic DCs also induce TGF-beta1 secretion in the mediastinal lymph nodes, which results in expansion of Foxp3 ( + ) T ( regs )
Zheng et al., Parasite Immunol 2010 (Malaria) : In contrast, susceptible BALB/c mice produced more plasmacytoid ( CD11c ( + ) CD45R/B220 ( + ) ) and less mature DCs , resulting in high levels of IL-10 and TGF-beta1