Gene interactions and pathways from curated databases and text-mining

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INS — KCNJ4

Text-mined interactions from Literome

Wolff et al., Comb Chem High Throughput Screen 2006 : Upon stimulation of the hIR with insulin-like growth factor-1 (IGF-1) , PI3K was activated to phosphorylate phosphatidylinositol ( PtdIns ) -4,5-bisphosphate at the 3-position, resulting in the recruitment of AKT1-EGFP to the plasma membrane
Feuerstein et al., Exp Cell Res 1991 : In vivo and in vitro phosphorylation studies of numatrin, a cell cycle regulated nuclear protein, in insulin stimulated NIH 3T3 HIR cells
McClain et al., J Biol Chem 1990 : It is shown in the present study that hIR delta ex16 receptors do mediate insulin action
Tobe et al., J Biol Chem 1993 : Incubation of an ASH fusion protein with the lysates of insulin stimulated CHO-HIR cells revealed that the fusion protein of ASH was able to bind the tyrosine phosphorylated 170-kDa protein that was recognized by alpha IRS-1
Ahn et al., J Biol Chem 1993 : After stimulation of CHO/HIR or CHO/HIRT1336N cells with insulin , the wild type and mutant receptors internalized the hormone and were down-regulated with similar rates