Yang et al., Cytokine 2009
(Ovarian Neoplasms) :
The effect of IL-6 and IL-8 on activation of estrogen-responsive promoter as well as estrogen receptor (ER)alpha and ER beta expression was also analyzed
Danforth et al., Cancer Res 1993
(Breast Neoplasms) :
IL-1 or IL-6 alone each down-regulated the estrogen receptor ( 36.7 %, P < 0.01, and 23.2 %, P < 0.05, respectively ), but the combination IL-1 + IL-6 did not cause a significantly greater effect than IL-1 alone
Ray et al., FEBS Lett 1997
(Adenocarcinoma...) :
We previously showed that inhibition of IL-6 gene expression by E2 does not involve high-affinity binding of the estrogen receptor ( ER ) to IL-6 DNA