◀ Back to POLDIP2

MAP3K4 — POLDIP2

Text-mined interactions from Literome

Chi et al., EMBO J 2004 (MAP Kinase Signaling System) : Thus, MEKK4 mediates the action of GADD45beta and GADD45gamma on p38 activation and IFNgamma production
Sun et al., Oncol Rep 2011 : MEKK1/MEKK4 are responsible for TRAIL induced JNK/p38 phosphorylation ... We found that MEKK1/MEKK4 as opposed to ASK1, are responsible for TRAIL induced c-Jun NH2-terminal kinase (JNK) or p38 activation, and that their catalytic activity is repressed by the caspase-8 inhibitor, suggesting that the caspase-8 activation induced by TRAIL is indispensible for MEKK activation