Thomas et al., Am J Physiol 1991
:
Thus a pertussis toxin-sensitive GTP binding protein is involved in the activation of PLC by ET in glomerular mesangial cells
Yada et al., FEBS Lett 1989
:
These findings suggest that a GTP binding protein is involved in the GTP gamma S-mediated activation of PLC and that cAMP ( plus A-kinase ) inhibits this activation by phosphorylating a membrane protein ( probably a 240-kDa protein ), rather than the GTP binding protein or PLC itself
Katsura et al., Behav Brain Res 1997
:
These results suggest that vinconate may induce the facilitation of phosphatidylinositide ( PI ) turnover via the stimulation of muscarinic acetylcholine receptors, the enhancement of coupling between muscarinic acetylcholine receptors and GTP binding protein , and the direct activations of PIP2-specific and cytosolic PLC