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GJA1 — WNT1

Text-mined interactions from Literome

Ai et al., J Clin Invest 2000 : Wnt-1 regulation of connexin43 in cardiac myocytes
Du et al., Cell communication & adhesion 2008 : Lithium chloride regulates connexin43 in skeletal myoblasts in vitro : possible involvement in Wnt/beta-catenin signaling
van der Heyden et al., J Cell Sci 1998 (Carcinoma, Embryonal) : Also, induction of Wnt1 expression in a mammary epithelial cell line leads to an increase in gap-junctional communication and Cx43 protein expression ... In transient transactivation assays in P19 EC cells we found that Wnt1 and Li+, an ion that mimics Wnt signalling, increased transcription from the rat Cx43 promoter, potentially via TCF/LEF binding elements, in a pathway separate from cAMP induced Cx43 transactivation ... The results demonstrate that Cx43 acts as a functional target of Wnt1 signalling, and Cx43 expression can be regulated by Wnt1 at the transcriptional level