Gene interactions and pathways from curated databases and text-mining

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CLU — TGFB1

Text-mined interactions from Literome

Wegrowski et al., Exp Cell Res 1999 : The activator protein-1 binding site partly directed the TGFbeta1 stimulated clusterin expression
Zenkel et al., Invest Ophthalmol Vis Sci 2006 (Exfoliation Syndrome...) : Real-time PCR and Western blot analysis were used to study the effect of TGF-beta1 , which is significantly increased in the aqueous humor of PEX eyes, on clusterin expression by nonpigmented ciliary epithelial cells in vitro
Itahana et al., Exp Cell Res 2007 : On the other hand, the second and most dramatic up-regulation of clusterin can be due to the potent induction by TGF-beta1 , and this up-regulation by TGF-beta1 is dependent on beta1 integrin ligand binding activity
Jurkunas et al., Invest Ophthalmol Vis Sci 2009 (Fuchs' Endothelial Dystrophy) : Colocalization of increased transforming growth factor-beta induced protein ( TGFBIp ) and Clusterin in Fuchs endothelial corneal dystrophy
Morgan et al., J Neuroimmunol 1995 : This study characterizes the effect of transforming growth factor (TGF) beta 1 on clusterin expression in rat brain cells ... However, in cultures of astrocytes that contained microglia and oligodendrocytes ( mixed glia cultures ), TGF-beta 1 caused a dose dependent increase in astrocytic clusterin mRNA levels ... TGF-beta 1 increased clusterin protein in the conditioned medium from cultured glia, in either monotypic or mixed glial cultures
Laping et al., J Am Soc Nephrol 1997 : Epidermal growth factor, insulin-like growth factor-1, and transforming growth factor-beta 1 had little or no effect on clusterin mRNA levels