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RHOA — SRGN
Text-mined interactions from Literome
Broggini et al., Mol Biol Cell 2010
:
Moreover, axon collapse and
RhoA activation induced by LPA and myelin associated neurite inhibitor Nogo-A is attenuated in the
presence of
PRG5 , although direct activation of the RhoA-Rho-PIP5K kinase pathway abolishes PRG5 -formed neurites
Bielnicki et al., J Biol Chem 2011
:
PDZRhoGEF (PRG) belongs to a small family of RhoA-specific nucleotide exchange factors that mediates signaling through select G-protein coupled receptors via Ga ( 12/13 ) and
activates RhoA by catalyzing the exchange of GDP to GTP