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PCBD1 — TGFB1
Text-mined interactions from Literome
Motyl et al., Cell Mol Biol Incl Cyto Enzymol 2000
:
Prolactin protected HC11 cells against
TGF-beta1 induced
PCD , which could occur at two levels : 1 ) TGF-beta1 expression, through the decrease of TGF-beta1 transcript content, and 2 ) Bax/Bcl-2 checkpoint, through down-regulation of Bax and up-regulation of Bcl-2
Chen et al., Chin Med J (Engl) 1998
(Cystadenocarcinoma, Papillary...) :
TGF beta 1 can not only act as an autocrine to inhibit cell proliferation, but also
trigger PCD in HO-8910 cells
Dünker et al., Development 2001
:
We have shown that reduction of endogenous
transforming growth factor beta ( TGF-beta )
prevents apoptotic
PCD of neurons in the developing peripheral and central nervous system, suggesting that TGF-beta is an important mediator of ontogenetic neuron death