Gene interactions and pathways from curated databases and text-mining

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PCBD1 — TGFB1

Text-mined interactions from Literome

Motyl et al., Cell Mol Biol Incl Cyto Enzymol 2000 : Prolactin protected HC11 cells against TGF-beta1 induced PCD , which could occur at two levels : 1 ) TGF-beta1 expression, through the decrease of TGF-beta1 transcript content, and 2 ) Bax/Bcl-2 checkpoint, through down-regulation of Bax and up-regulation of Bcl-2
Chen et al., Chin Med J (Engl) 1998 (Cystadenocarcinoma, Papillary...) : TGF beta 1 can not only act as an autocrine to inhibit cell proliferation, but also trigger PCD in HO-8910 cells
Dünker et al., Development 2001 : We have shown that reduction of endogenous transforming growth factor beta ( TGF-beta ) prevents apoptotic PCD of neurons in the developing peripheral and central nervous system, suggesting that TGF-beta is an important mediator of ontogenetic neuron death