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HIF1A — NR4A1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Yoo et al., J Biol Chem 2004
(Anoxia...) :
Finally, PD98059 decreased Nur77 induced HIF-1alpha stability and recovered MDM2 expression, indicating that the extracellular signal regulated kinase pathway is critical in the
Nur77 induced activation of
HIF-1alpha
Kim et al., Exp Mol Med 2008
:
Moreover,
Nur77 binding to pVHL inhibited the pVHL mediated ubiquitination of HIF-1alpha and ultimately
increased the stability and transcriptional activity of
HIF-1alpha