Sweet et al., J Cell Physiol 2005
:
In the absence of the kappaB binding sites, NFBP augments the TAR dependent activation by Tat , yet it interferes with the synergistic effect of P65 and Tat on LTR transcription
Purvis et al., AIDS Res Hum Retroviruses 1995
(HIV Infections) :
Tat induced programmed cell death may contribute to the lymphocyte depletion seen in persons infected with HIV-1
Patki et al., Cell Immunol 1996
:
To explore further the effects of the HIV-1 transactivator protein Tat on human lymphoid cell function we examined the effects of Tat on lymphocyte proliferation and programmed cell death ( apoptosis )