Gene interactions and pathways from curated databases and text-mining

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IL37 — IL4

Text-mined interactions from Literome

De Caterina et al., Am J Clin Nutr 2000 (Arteriosclerosis) : Consumption of the n-3 fatty acid docosahexaenoic acid ( DHA ; 22 : 6n-3 ) reduced endothelial expression of vascular cell adhesion molecule 1 ( VCAM-1 ), E-selectin, intercellular adhesion molecule 1 ( ICAM-1 ), interleukin 6 (IL-6), and IL-8 in response to IL-1, IL-4 , tumor necrosis factor, or bacterial endotoxin, with a half-maximal inhibitory concentration ( IC ( 50 ) ) of 1-25 micromol, ie, in the range of nutritionally achievable plasma concentrations
Trindade et al., J Orthop Res 1999 : Interleukin-4 inhibits granulocyte-macrophage colony stimulating factor, interleukin-6 , and tumor necrosis factor-alpha expression by human monocytes in response to polymethylmethacrylate particle challenge in vitro ... Interleukin-4 inhibited the expression of granulocyte-macrophage colony stimulating factor, interleukin-6 , and tumor necrosis factor-alpha at 48 hours in a dose dependent manner
Roy et al., Surgery 2000 : Interleukin-4 regulates macrophage interleukin-12 protein synthesis through a c-fos mediated mechanism
Bonder et al., Cytokine 2002 : While IL-4 can suppress LPS induced interleukin beta ( IL-beta ) and tumour necrosis factor alpha (TNF-alpha) production by monocytes, IL-4 can suppress LPS induced IL-1 beta, but not TNFalpha production by the more differentiated cells
Rollier et al., J Virol 2004 (Hepatitis C, Chronic) : Immunization induced antibodies, peptide-specific gamma interferon ( IFN-gamma ), protein-specific lymphoproliferative responses, IFN-gamma, interleukin-2 (IL-2), and IL-4 T-helper responses in both vaccinees
Raes et al., J Leukoc Biol 2005 (Asthma...) : In addition, we demonstrate that in vitro, interleukin-4 (IL-4) and IL-13 up-regulate mMGL1 and mMGL2 expression and that in vivo, induction of mMGL1 and mMGL2 is dependent on IL-4 receptor signaling
Melk et al., Transplantation 2004 (Growth Disorders...) : During rhGH therapy in children with transplants, interleukin (IL)-2 production increased threefold at 4 weeks, and IL-4 and IL-13 increased by 70 % at 12 weeks
Bouchelouche et al., J Urol 2006 : Interleukin-4 and 13 induce the expression and release of monocyte chemoattractant protein 1, interleukin-6 and stem cell factor from human detrusor smooth muscle cells : synergy with interleukin-1beta and tumor necrosis factor-alpha
Xing et al., Chin Med J (Engl) 2011 (Alzheimer Disease) : Ex vivo cultured splenocytes isolated from mice immunized with p ( Aß ( 3-10 ) ) ( 10 ) -CpG exhibited high interleukin-4 response and low interleukin-? ( IFN-? ) response
Uchiyama et al., Journal of cardiothoracic surgery 2012 : Proliferation of splenocytes, interleukin (IL)-2 and interferon ( IFN ) -? production was suppressed in opera exposed mice, and production of IL-4 and IL-10 from opera exposed transplant recipients increased compared to that from splenocytes of untreated recipients
Weiss et al., Eur J Immunol 1989 : Human T cells and interleukin 4 inhibit the release of interleukin 1 induced by lipopolysaccharide in serum-free cultures of autologous monocytes
Hurme et al., Biochem Biophys Res Commun 1988 : Interleukin-4 inhibits interleukin-1 synthesis by a posttranscriptional mechanism ... Interleukin-4 had a clear dose dependent suppressive effect on the interleukin-1 synthesis
Benveniste et al., Proc Natl Acad Sci U S A 1996 (Acute Disease...) : Comparative interleukin ( IL-2 ) /interferon IFN-gamma and IL-4/IL-10 responses during acute infection of macaques inoculated with attenuated nef truncated or pathogenic SICmac251 virus
Salvucci et al., Eur J Immunol 1996 : Differential regulation of interleukin-12- and interleukin-15 induced natural killer cell activation by interleukin-4
Gollob et al., Eur J Immunol 1997 : Interferon-gamma and interleukin-4 regulate T cell interleukin-12 responsiveness through the differential modulation of high-affinity interleukin-12 receptor expression