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GNA12 — IFI44

Text-mined interactions from Literome

Ghahremani et al., Mol Cell Biol 2000 (Cell Transformation, Neoplastic) : This approach identified Galpha(i)2 and Galpha(i)3 as mediators of the D2S receptor mediated inhibition of forskolin stimulated adenylyl cyclase activity ; Galpha(i)2 mediated D2S induced stimulation of p42 and p44 mitogen activated kinase ( MAPK ) and DNA synthesis, whereas Galpha(i)3 was required for formation of transformed foci
Kinane et al., Am J Physiol 1997 : Expression of a guanosinetriphosphatase ( GTPase ) -deficient G alpha(i-2) in these cells increased MAPK ( p42/p44 ) activity and correspondingly reduced cell doubling time from 24 to 10 h without altering the activity of Raf-1 or c-Jun/stress activated protein kinases ( SAPKs )