Gene interactions and pathways from curated databases and text-mining

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FUT1 — PDGFB

Text-mined interactions from Literome

Paradis et al., Lab Invest 2002 : Furthermore, spontaneous activation of HSC plated on plastic and stimulation by vascular endothelial growth factor, lipid peroxidation products ( HNE, MDA ), acetaldehyde, and platelet derived growth factor (PDGF)-BB significantly up-regulated CTGF mRNA expression in HSC
Breitkopf et al., Cytokine 2005 (Fibrosis) : Stimulation of HSC and MFB with PDGF-BB led to down-regulation of the new isoforms, whereas TGF-beta1 upregulated PDGF-A only
Li et al., Zhonghua Gan Zang Bing Za Zhi 2005 : Stimulation of HSC by Aldo results in activation of EGR-1 via ERK1/2 pathway, leading to up-regulation of PDGF-B expression
Xue et al., Zhongguo Zhong Xi Yi Jie He Za Zhi 2006 : Expressions of extracellular regulated kinase (ERK) and its phosphorylation in HSC, and expressions of TGF beta1, receptor I ( TbetaR I ) and II ( TbetaR II ) and PDGF receptor beta ( PDGFR-beta ) on the surface of HSC induced by TGF-beta1 or PDGF-BB were detected with Western blot assay
Ogawa et al., Hepatology international 2009 : We found that interferon a inhibited serum stimulated [ ( 3 ) H ] thymidine incorporation of HSC in a dose dependent manner, with a significant reduction at more than 100 U/ml. Interferon a also attenuated PDGF-BB stimulated DNA synthesis of HSC