Wahab et al., J Am Soc Nephrol 2005
:
K252a, a known selective inhibitor of Trk, blocked this phosphorylation, CTGF induced activation of signaling proteins, and CTGF dependent induction of the transcription factor TGF-beta-inducible early gene in HMC
Plotkin et al., J Cell Biochem 2008
:
Suppression of Pod1 by siRNA resulted in increased cell proliferation and reduced expression of alphaSMA, fibronectin, and CTGF , and myofibroblast secreted proteins including pro-fibrotic cytokines and inhibitors of matrix metalloproteinases