Gene interactions and pathways from curated databases and text-mining

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CD40LG — MYC

Text-mined interactions from Literome

Donjerković et al., Cell Growth Differ 1999 (Lymphoma, B-Cell) : This down-regulation of c-Myc is prevented by CD40L , which rescues cells from anti-IgM induced apoptosis
Daumer et al., J Bone Miner Res 2002 : Both v-Myc and c-Myc negatively regulated transcription from the TRAP promoter in P388D1 and C3H10T1/2 cells, 90 % and 50 %, respective to cell type and amount of endogenous Myc protein, and delta84/NLS had no effect ... This report provides the first evidence of the specific regulation of TRAP at the transcriptional level by Myc , a transcription factor that is normally expressed at relatively high levels in preosteoclasts and other myelomonocytic cells and suggests that Myc plays an active role in suppressing the transcription of a mature osteoclast selective gene