◀ Back to CASP8
CASP8 — IL1RN
Text-mined interactions from Literome
Maedler et al., Proc Natl Acad Sci U S A 2004
(Diabetes Mellitus, Type 2) :
Antagonizing
IL-1Ra by introduction of small interfering RNA to IL-1Ra into human islets
led to
caspase-3 activation, DNA fragmentation, and impaired beta cell function
Taylor et al., AIDS 2010
(HIV Infections) :
Furthermore,
Casp8p41 expression in primary CD4 T cells
results in increased production of interleukin (IL)-2, IL-15 and tumor necrosis factor (TNF), as well as
IL-1RA ; whereas levels of granulocyte macrophage colony stimulating factor and interferon (IFN)-gamma were reduced in the Casp8p41 expressing cells
Maron-Gutierrez et al., Eur Respir J 2011
(Pulmonary Fibrosis...) :
Nevertheless,
caspase-3 , IL-1ß, IL-1a,
IL-1RN and TGF-ß mRNA expression
diminished after cell therapy