Gene interactions and pathways from curated databases and text-mining

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IL6 — MPL

Text-mined interactions from Literome

MacLeod et al., Proc Natl Acad Sci U S A 2011 (Orthomyxoviridae Infections) : MPL induced IL-6 was required for cytotoxic differentiation
Cao et al., J Med Food 2012 : Meanwhile, compared with the control group, not only the mRNA expressions of tumor necrosis factor-a (TNF-a), interleukin-6 (IL-6) , and interferon-? ( IFN-? ) in macrophages, but also the productions of proteins, were strongly induced by MPL ; these effects were inhibited by pyrrolidine dithiocarbamate
Lee et al., J Clin Immunol 2013 (MAP Kinase Signaling System) : After investigating transfections of the NF-?B and NF-IL6 reporter vectors, NF-IL6 activation was significantly induced by MPL stimulation, which was considerably decreased by U0126 and monoclonal anti-TLR2 antibody