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ID1 — MYC
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Swarbrick et al., Oncogene 2005
(Breast Neoplasms) :
Inhibition of
c-Myc function by siRNA, antisense oligonucleotides or a dominant repressor
resulted in downregulation of
Id1 , while ectopic expression of c-Myc resulted in rapid induction of Id1, suggesting that Id1 may be downstream of c-Myc
Rothschild et al., Oncogene 2012
(Adenocarcinoma...) :
Saracatinib and dasatinib decreased c-Myc transcriptional repression on miR-29b and led to increased ID1 protein levels, whereas forced expression of
c-Myc repressed miR-29b and
induced ID1