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PTGS2 — SLC22A3
Text-mined interactions from Literome
Neil et al., Carcinogenesis 2008
:
Cox-2 inactivates Smad signaling and
enhances EMT stimulated by TGF-beta through a PGE2 dependent mechanisms ... Moreover, stable
Cox-2 expression in normal MECs
stimulated their invasion,
EMT and anchorage independent growth and inhibited their activation of Smad2/3 by TGF-beta
Adhim et al., Br J Cancer 2011
(Urinary Bladder Neoplasms) :
In this study, we investigated the
effect of
Cox-2 inhibitors on reversal
EMT and tumour growth inhibition in bladder cancer cells