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APCS — IL2

Text-mined interactions from Literome

Chou et al., J Immunol 2005 (Berylliosis...) : Our results demonstrate that in the presence of APCs , beryllium induced strong proliferation responses of BAL CD4 ( + ) T cells, production of superoptimal concentrations of secreted proinflammatory cytokines, IFN-gamma, TNF-alpha, and IL-2 , and up-regulation of numerous T cell surface markers that would promote T-T Ag presentation
Kim et al., Ann N Y Acad Sci 2006 (Colitis, Ulcerative) : Antigen presenting cells (APCs) lacking B7-1 or B7-2 stimulated T cell proliferation in vitro, but caused suboptimal IL-2 production, leading to decreased induction of CTLA-4
Cao et al., Zhonghua Xue Ye Xue Za Zhi 2009 : Upon stimulation with anti-CD3 epsilon and APCs , the proliferative capacity of Foxp3 transduced T cells and the production of IL-2 , IL-4, IL-10, IFN-gamma were significantly lower than those in control group ( P < 0.01 ) ; Foxp3 transduced T cells also significantly inhibited the proliferation of CD4 ( + ) CD25 ( - ) T cells
Keller et al., Clin Exp Allergy 2010 (Hypersensitivity, Delayed) : We identified two mechanisms of T cell stimulation : some TCCs and the transfectant reacted to CM independent of uptake by APCs because proliferation/IL-2 secretion occurred in the presence of glutaraldehyde fixed APCs , and intracellular calcium increased within seconds after drug addition
Ji et al., Immunol Cell Biol 2012 (Encephalomyelitis, Autoimmune, Experimental...) : In vitro, SAP suppressed the secretion of interleukin-2 stimulated by P-selectin and blocked P-selectin binding to T cells
Meier et al., Eur J Biochem 1996 : SAPKK-4 was the only SAP kinase-1 activator induced by interleukin-1 or ultraviolet irradiation, while two SAP kinase-1 activators, SAPKK-1 and SAPKK-5, were induced by osmotic shock or anisomycin
Sad et al., J Immunol 1997 : IL-2 synthesis was the most sensitive, as stimulation of IL-4 treated Tc1 cells with higher numbers of APCs partially restored IFN-gamma, TNF, and IL-10, but not IL-2 , synthesis