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CASP8 — HIP1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: HIP1 — CASP8 (physical association, affinity chromatography technology) Gervais et al., Nat Cell Biol 2002*
• IRef Hprd Interaction: CASP8 — HIP1 (in vivo) Gervais et al., Nat Cell Biol 2002*
• IRef Hprd Interaction: Complex of HIP1-CASP8-IFT57-CASP8-HIP1-IFT57-HIP1-CASP8-IFT57 (in vivo) Gervais et al., Nat Cell Biol 2002*
• IRef Ophid Interaction: CASP8 — HIP1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Gervais et al., Nat Cell Biol 2002 (Huntington Disease) : Recruitment and activation of caspase-8 by the Huntingtin interacting protein Hip-1 and a novel partner Hippi
Wanker et al., Dev Cell 2002 (Huntington Disease) : Biochemical and cell biological studies point to a role for Hip1 and Hippi in caspase-8 activation and the initiation of apoptosis during the pathogenesis of Huntington 's disease
Banerjee et al., Nucleic Acids Res 2010 : Taking together, we are able to show the importance of R393 of HIPPI and the role of HIPPI-HIP-1 heterodimer in the transcription regulation of caspase-1