◀ Back to CDH1

CD44 — CDH1

Text-mined interactions from Literome

Xu et al., J Biol Chem 2003 (Neoplasm Invasiveness) : E-cadherin negatively regulates CD44-hyaluronan interaction and CD44 mediated tumor invasion and branching morphogenesis ... The results reported here demonstrated for the first time that E-cadherin negatively regulated CD44-HA interaction and CD44 function and suggested that balanced function of CD44 and E-cadherin may be essential for normal epithelial cell functions, and imbalanced up-regulation of CD44 function and/or down-regulation of E-cadherin function likely contributes to tumor progression
Wang et al., Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2004 (Lymphatic Metastasis...) : In the group of nasopharyngeal carcinoma with distant metastasis, the expression of E-cadherin and nm23H1 also increased and the expression of CD44H , MMP-3 and VEGF all increased
Bao et al., J Cell Biochem 2011 (Pancreatic Neoplasms) : Moreover, over-expression of FoxM1 led to the acquisition of EMT phenotype by activation of mesenchymal cell markers, ZEB1, ZEB2, Snail2, E-cadherin , and vimentin, which is consistent with increased sphere forming ( pancreatospheres ) capacity and expression of CSC surface markers ( CD44 and EpCAM )