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GRAP2 — PPARGC1A
Text-mined interactions from Literome
Akimoto et al., J Biol Chem 2005
(MAP Kinase Signaling System) :
Furthermore, the
p38 mediated increase in
Pgc-1alpha promoter activity was enhanced by increased expression of the downstream transcription factor ATF2 and completely blocked by ATF2DeltaN, a dominant negative ATF2
Luo et al., J Mol Neurosci 2009
(Reperfusion Injury) :
Furthermore, increase of
PGC-1alpha resulted in activation of N-methyl-D-aspartate ( NMDA ) receptor,
p38 , and ERK mitogen activated protein kinase ( MAPK ) pathway ... At the same time, PD98059 ( ERK MAPK inhibitor ) and SB203580 ( P38 MAPK inhibitor ) also prevented the up-regulation of
PGC-1alpha in OGD neurons and MK801 can
inhibit the expression of
P38 and ERK MAPK
Pogozelski et al., PloS one 2009
(MAP Kinase Signaling System...) :
Gene transfer
mediated overexpression of a dominant negative form of
p38gamma , but not that of p38alpha or p38beta, blocked motor nerve stimulation induced
Pgc-1alpha transcription