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JAG1 — TNF
Text-mined interactions from Literome
Park et al., Biochem Biophys Res Commun 2001
(Cell Transformation, Neoplastic) :
In TSU-Pr1 and T24 ( oncogenic Ras cell lines ), TNF-alpha suppresses cell cycle progression without induction of apoptosis, whereas
AGS ( wild-type Ras ) is
stimulated in its cell cycle by
TNF-alpha coupled with activation of Erk
Anguita et al., J Immunol 2002
(Arthritis, Infectious...) :
B. burgdorferi
Ags activated p38 MAP kinase in vitro, and the use of a specific inhibitor
repressed the spirochete induced production of
TNF-alpha
Mangada et al., J Immunol 2005
:
IFN-gamma and
TNF-alpha responses to inactivated DEN
Ags were detected in up to 0.54 and 1.17 % of total circulating CD4+ T cells, respectively
Sainson et al., Blood 2008
(Inflammation) :
Notch signaling regulates tip cell function, and we find that
TNF also
induces the notch ligand
jagged-1 , through an NFkappaB dependent mechanism
Johnston et al., Gene 2009
:
TNF induction of
jagged-1 in endothelial cells is NFkappaB dependent ... Here we demonstrate that
TNF induction of
jagged-1 in human EC is rapid and dependent upon signaling through TNFR1, but not TNFR2 ... These results indicate that canonical NFkappaB signaling is required for
TNF induction of the notch ligand
jagged-1 in EC
Commandeur et al., J Immunol 2013
(Disease Models, Animal...) :
Finally, IVE-TB
Ags induced strong IFN-? ( + )
/TNF-a ( + ) CD8 ( + ) and TNF-a ( + ) /IL-2 ( + ) CD154 ( + ) /CD4 ( + ) T cell responses in PBMC from long-term latently M. tuberculosis infected individuals