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EGFR — F2RL1

Text-mined interactions from Literome

Caruso et al., Am J Pathol 2006 (Adenocarcinoma...) : In both these cell lines, PAR-2 trans activated EGFR and inhibition of EGFR tyrosine kinase activity by AG1478 or specific EGFR siRNA completely prevented PAR-2-driven proliferation
Jarry et al., Biochem Biophys Res Commun 2007 (Calcium Signaling) : PAR-2 activation increases human intestinal mucin secretion through EGFR transactivation ... Inhibitors of MAPK activation ( PD98059 ) and EGFR tyrosine kinase activity ( AG1478 ) abrogated PAR-2 induced ERK1/2 and EGFR tyrosine phosphorylation, respectively, and subsequent mucin secretion ... Finally, PAR-2 induced EGFR transactivation was involved upstream of ERK1/2 activation
Heijink et al., Eur Respir J 2010 : HDM promoted redistribution of E-cadherin was mediated via EGFR dependent activation of protease activated receptor (PAR)-2 , while the concomitant ZO-1 degradation was PAR-2/EGFR independent