Gene interactions and pathways from curated databases and text-mining

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AGTR1 — LEP

Text-mined interactions from Literome

Sonmez et al., J Renin Angiotensin Aldosterone Syst 2001 (Hypertension) : We conclude that leptin levels are not affected by AT1-receptor blockade and are not related to T-cell activity
Hilzendeger et al., Am J Physiol Heart Circ Physiol 2012 (Body Weight) : ICV leptin in rats increased AT(1a)R and angiotensin converting enzyme (ACE) mRNA in the subfornical organ and AT(1a)R mRNA in the arcuate nucleus, suggesting leptin induced upregulation of the brain RAS in specific brain regions