Gene interactions and pathways from curated databases and text-mining

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ERVK-6 — ITCH

Text-mined interactions from Literome

Tsujii et al., J Pharmacol Sci 2009 (Chronic Disease...) : These results suggest that PAR(2) and serine proteinase ( s ), mainly tryptase, are involved in the itch of chronic dermatitis
Hostetler et al., The Journal of clinical and aesthetic dermatology 2010 : A subpopulation of patients may have cutaneous exposure to common airborne proteins exacerbating their disease through direct proteolytic activity, direct activation of proteinase activated receptor-2 itch receptors, and immunoglobulin E binding