Parameswaran et al., J Biol Chem 2006
:
Here, we demonstrate that arrestin-2 and GRK5 ( G protein coupled receptor kinase 5 ), proteins that regulate G protein coupled receptor signaling, play a negative role in TLR4 signaling in Raw264.7 macrophages
Packiriswamy et al., Cell Immunol 2012
(Systemic Inflammatory Response Syndrome) :
Together, our results demonstrate multiple roles of GRK5 in TLR signaling