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Aikawa et al., J Cell Biol 2003
:
Increased Ca2+ and dephosphorylation stimulated the association of PIP5KIgamma with ARF6
Vasudevan et al., J Cell Sci 2009
(Calcium Signaling) :
In summary, PIP5K-I gamma positively regulates antigen stimulated Ca2+ release from ER stores, whereas PIP5K-I beta negatively regulates store operated Ca2+ entry, suggesting that these different PIP5K-I isoforms synthesize functionally distinct pools of PtdIns ( 4,5 ) P2 at the plasma membrane