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ANGPT2 — TCF7

Text-mined interactions from Literome

Reddy et al., American journal of physiology. Renal physiology 2002 (Diabetic Nephropathies...) : ANG II and 12 ( S ) -HETE led to activation of p38 ( MAPK ) and its target transcription factor cAMP-responsive element binding protein ( CREB )
McAllister-Lucas et al., Proc Natl Acad Sci U S A 2007 (Inflammation) : Much of this effect of Ang II results from activation of the proinflammatory NF-kappaB transcription factor in response to stimulation of the type 1 Ang II receptor, a G protein coupled receptor
Singh et al., Journal of signal transduction 2011 : These findings suggest that intracellular Ang II increases TGF-b1 and matrix in human mesangial cells and also activates Stat3 transcription factor without involvement of the extracellular Ang II signaling pathway
Yu et al., Int J Mol Med 2013 : Further experiments revealed that Ang II increased the level of the phosphorylated form of the transcription factor, nuclear factor ?-light-chain-enhancer of activated B cells ( NF-?B ), as well as NF-?B-DNA binding activity in the cardiomyocytes ; treatment with TMP significantly inhibited the Ang II induced activation of NF-?B
Kudoh et al., Circ Res 1997 : In the present study, to elucidate the mechanism by which Ang II regulates gene expression in cardiac myocytes, we examined whether Ang II activates c-Jun NH2-terminal kinase (JNK), which is a member of the mitogen activated protein kinase family and activates the transcription factor , activator protein-1 (AP-1)