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CREB1 — CYP19A1

Text-mined interactions from Literome

Sofi et al., Breast Cancer Res Treat 2003 (Breast Neoplasms) : Role of CRE binding protein ( CREB ) in aromatase expression in breast adipose
Sirianni et al., J Biol Chem 2009 : Inhibitors for COX-2 ( NS398 ), EP4 ( AH23848 ), and PKA ( H89 ) decreased aromatase expression and activity as a consequence of a decreased phosphorylated CREB recruitment to the PII promoter of the aromatase gene
Brown et al., Cancer Res 2010 (Breast Neoplasms...) : In postmenopausal women, the CREB dependent regulation of aromatase is a crucial determinant of breast tumor formation through local production of estrogens
Carlone et al., Mol Endocrinol 1997 : Taken together, the data indicate that expression of the aromatase gene is dependent on the additive interactions of regions A and B of the aromatase promoter in granulosa cells and the synergistic interactions of these same regions in R2C cells and that these interactions are dependent , in turn, on the phosphorylation of CREB and SF-1 and the content of these factors, as well as the presence of putative coregulatory molecules