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HSPG2 — TGFB1
Text-mined interactions from Literome
Zhang et al., Blood 2004
:
The importance of perlecan expression levels in mediating the antiproliferative effect of the antiangiogenic antithrombins was suggested by the finding that
transforming growth factor-beta 1 , a potent stimulator of perlecan expression in endothelial cells,
blocked the down-regulation of
perlecan expression and antiproliferative activity of cleaved antithrombin on endothelial cells
Yung et al., J Am Soc Nephrol 2004
:
Reduction of
perlecan synthesis and
induction of
TGF-beta1 in human peritoneal mesothelial cells due to high dialysate glucose concentration : implication in peritoneal dialysis
Uttamsingh et al., Oncogene 2008
(Cell Transformation, Neoplastic) :
Phospholipase C (PLC) and Cox2
induced by EGF plus
TGF-beta1 also played a significant role in invasion, whereas PLC was also important for colony formation
Halstead et al., J Biol Chem 1995
:
Further, D609, an inhibitor of phosphatidylcholine-phospholipase C (
PC-PLC ), and secondarily PKC also
blocks TGF-beta 1-induced transcription of the transgene in A549 cells while the phosphatidylinositol-PLC pathway inhibitor U73122 is without effect