Gene interactions and pathways from curated databases and text-mining

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HSPG2 — TGFB1

Text-mined interactions from Literome

Zhang et al., Blood 2004 : The importance of perlecan expression levels in mediating the antiproliferative effect of the antiangiogenic antithrombins was suggested by the finding that transforming growth factor-beta 1 , a potent stimulator of perlecan expression in endothelial cells, blocked the down-regulation of perlecan expression and antiproliferative activity of cleaved antithrombin on endothelial cells
Yung et al., J Am Soc Nephrol 2004 : Reduction of perlecan synthesis and induction of TGF-beta1 in human peritoneal mesothelial cells due to high dialysate glucose concentration : implication in peritoneal dialysis
Uttamsingh et al., Oncogene 2008 (Cell Transformation, Neoplastic) : Phospholipase C (PLC) and Cox2 induced by EGF plus TGF-beta1 also played a significant role in invasion, whereas PLC was also important for colony formation
Halstead et al., J Biol Chem 1995 : Further, D609, an inhibitor of phosphatidylcholine-phospholipase C ( PC-PLC ), and secondarily PKC also blocks TGF-beta 1-induced transcription of the transgene in A549 cells while the phosphatidylinositol-PLC pathway inhibitor U73122 is without effect