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ANXA6 — IL6

Text-mined interactions from Literome

Shi et al., J Biol Chem 2002 (MAP Kinase Signaling System...) : IL-6 rapidly activated p70 kinase activity and p70 phosphorylation ... Prevention of IL-6 induced p70 activation and 4E-BP1 phosphorylation by the mammalian target of rapamycin inhibitors rapamycin and CCI-779 resulted in inhibition of IL-6 induced myeloma cell growth ... These results indicate that both ERK and PI3-K/AKT pathways are required for optimal IL-6 induced p70 activity, but PI3-K/AKT is sufficient for 4E-BP1 phosphorylation
Shi et al., Mol Cancer Ther 2003 (Multiple Myeloma) : FTIs were also able to abrogate the IL-6 proliferative response of WT ras expressing MM cells, and this was associated with inhibition of IL-6 induced activation of ERK, AKT, and p70
Tsunetsugu-Yokota et al., J Virol 2003 : The uptake of yeast VLPs induced DC maturation and enhanced cytokine production, notably, interleukin-12 p70
Ross et al., Infect Immun 2004 : CyaA significantly augmented LPS induced IL-6 and IL-10 and inhibited LPS-driven tumor necrosis factor alpha and IL-12p70 production from bone marrow derived DC and macrophages