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FGR — IGF1
Pathways - manually collected, often from reviews:
-
WikiPathways Focal Adhesion:
EGF/FIGF/HGF/IGF1/PDGFA/PDGFB/PGF/PDGFC/PDGFD/VEGFA/VEGFB/VEGFC
→
BLK/EGFR/ERBB2/FGR/FLT1/HCK/IGF1R/KDR/MET/PDGFRA/PDGFRB/PTK6/SRMS/TXK/TESK2/STYK1/TNK2/TNK1
(activation)
Text-mined interactions from Literome
Randhawa et al., Mol Genet Metab 2005
:
In humans and mice, mutations or targeted deletions of the IGF ligands IGF1 and IGF2, as well as the
IGF type-I receptor and its main signaling molecule IRS1
lead to
FGR
Randhawa et al., Pediatr Endocrinol Rev 2008
(Fetal Growth Retardation...) :
In humans and mice, mutations or targeted deletions of the IGF ligands IGF1 and IGF2, as well as the
IGF type-1 receptor ( IGFR1 ) and its main signaling molecule IRS1
lead to
FGR