de Baey et al., Eur J Immunol 2001
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These DC produce IL-12p75 both in response to LPS and to CD40 ligation
Jiang et al., Mol Immunol 2008
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Furthermore, LPS induced upregulation of NGF and p75 ( NTR ) could be inhibited by p38MAPK inhibitor SB203580 and NF-kappaB inhibitor PDTC, suggesting TLR4 triggered activation of p38MAPK and NF-kappaB pathways are responsible for the process