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ANXA1 — TNF

Text-mined interactions from Literome

Tang et al., PloS one 2011 : The results show that Annexin A1 can negatively regulate phosphorylation of p38 and release of IL-1ß, IL-6 and TNF-a in THP-1 cells following propofol intervention and lipopolysaccharide (LPS) stimulation ... Our results clearly indicate that propofol can up-regulate Annexin A1 to inhibit the phosphorylation level of p38 and release of IL-1ß, IL-6 and TNF-a , so as to inhibit inflammatory response
Yang et al., J Immunol 2013 (Arthritis, Experimental...) : Similarly, experiments using AnxA1 ( -/- ) OT-II CD4 ( + ) T cells demonstrated that the absence of AnxA1 in T cells was sufficient to induce increased Ag-specific CD4 ( + ) T cell proliferation in vivo, augment T cell production of IFN-?, IL-17, TNF , and IL-6, and increase Akt, ERK, and p38 activation
Beidler et al., J Biol Chem 1995 : Additionally, p35 blocks TNF- and Fas induced proteolytic cleavage of the death substrate poly ( ADP-ribose ) polymerase from its native 116-kDa form to the characteristic 85-kDa form