Gene interactions and pathways from curated databases and text-mining

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IL2 — RBBP4

Text-mined interactions from Literome

Gray et al., Cytokine 2000 : Our results indicate that in contrast to the mouse, HDAC1 is not inducible by IL-2
Endt et al., Eur J Immunol 2007 : IL-2 stimulation leads to an up-regulation of SAP expression, which can be enhanced by IL-12, the stimulation of TLR3 by polyinosinic-polycytidylic acid ( poly ( I:C ) ) and to a lesser extent by IFN-alpha
Matsuoka et al., Biochem Pharmacol 2007 : Previous studies have shown that HDAC inhibitors selectively inhibit IL-2 gene expression, but the mechanism of this inhibition remains to be elucidated
Matsuoka et al., Biol Pharm Bull 2008 (Thrombocytopenia) : Histone deacetylase (HDAC) inhibitors repress interleukin-2 (IL-2) gene expression in T cells and possess immunosuppressive activity in vivo
Vitoriano-Souza et al., PloS one 2012 : With regard to cytokines, the SAP led to production of interleukin (IL)-2 , IL-6, and IL-4